With the aggravation of social aging and the increase in work intensity. the prevalence of spinal degenerative diseases caused by intervertebral disc degeneration(IDD)has increased yearly. which has driven a heavy economic burden on patients and society. It is well known that IDD is associated with cell damage and degradation of the extracellular matrix. https://www.ealisboa.com/limited-value-AXYS-Valhalla-Pen-must-buy/