In Parallel to characterising the interaction between conolidine and ACKR3, the two teams went a stage even more. The experts created a modified variant of conolidine — which they termed “RTI-5152-12” — which completely binds to ACKR3 with a fair greater affinity. Like LIH383, a patented compound previously designed by https://www.proleviate.com/post/conolidine-alkaloid-for-chronic-pain